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Bardoxolone Methyl
SPC-00328
CAS No. 218600-53-4
| Size | Price |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
IκB/IKK inhibitor ; Ferroptosis inhibitor ; Nrf2 activator ; Apoptosis related activator ; Autophagy activator ; NF-κB inhibitor
| Description |
|---|
| Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 218600-53-4 |
| Description | Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells. |
| Formula | C32H43NO4 |
| Molecular Weight | 505.69 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me |
| SMILES | CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)OC)C |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.