Axitinib - CD BioSciences

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Axitinib

Axitinib

SPC-00273

Axitinib

CAS No. 319460-85-0

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10 mM (1 mL in DMSO) Online Inquiry
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VEGFR inhibitor ; c-Kit inhibitor ; PDGFR inhibitor

Description
Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
Product Details
CAS No. CAS No. 319460-85-0
Description Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
Formula C22H18N4OS
Molecular Weight 386.47
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms AG 013736
SMILES CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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