Aurora A Inhibitor I (TC-S 7010) - CD BioSciences

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Aurora A Inhibitor I (TC-S 7010)

Aurora A Inhibitor I (TC-S 7010)

SPC-00262

Aurora A Inhibitor I (TC-S 7010)

CAS No. 1158838-45-9

Size Price
10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
50 mg Online Inquiry
Bulk Size Online Inquiry

Aurora Kinase inhibitor ; Apoptosis related activator

Description
Aurora A Inhibitor I (TC-S 7010) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.
Product Details
CAS No. CAS No. 1158838-45-9
Description Aurora A Inhibitor I (TC-S 7010) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.
Formula C31H31ClFN7O2
Molecular Weight 588.07
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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