ATF-4 Antibody - CD BioSciences

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ATF-4 Antibody

ATF-4 Antibody

SPA-00632

Size Price
0.05 mL Online Inquiry
0.025 mL Online Inquiry
More Options Online Inquiry
Target Information
Target Name ATF-4
Gene Abbr. ATF4
Gene ID 468
Full Name activating transcription factor 4
Alias CREB-2, CREB2, TAXREB67, TXREB
Introduction ATF-4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. E4Q4E
Immunogen Synthetic peptide corresponding to residues surrounding Pro134 of human ATF-4 protein.
Source/Purification Antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro134 of human ATF-4 protein.
Usage
Application WB, IF
Dilutions Western Blot (1:1000)
MW(KDa) 49
Reactivity Human
Sensitivity Endogenous
Specificity It recognizes endogenous levels of total ATF-4 protein.
Storage & Handling
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide.
Preservative Less than 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Do not aliquot the antibody.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.