Online Inquiry
Activin A (Inhibin beta B) Antibody
SPA-06018
| Size | Price |
| 0.1 mg | Online Inquiry |
| 0.025 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Inhibin |
| Gene Abbr. | INHBB |
| Gene ID | 3625 |
| Full Name | inhibin subunit beta B |
| Introduction | Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin and Inhibin are produced as precursor proteins. Their amino terminal propeptides are proteolytically cleaved and facilitate formation of disulfide-linked dimers of the bioactive proteins. Activins are nonglycosylated homodimers or heterodimers of various beta subunits ( beta A, beta B, beta C, and beta E in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two beta A chains. The beta A subunit can also heterodimerize with a beta B or beta C subunit to form Activin AB and Activin AC, respectively. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 146807 |
| Isotype | IgG1 |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant human Activin B. Gly293-Ala407. Accession # Q53T31. |
| Usage | |
|---|---|
| Application | WB |
| Dilutions | Western Blot (1 µg/mL); Neutralization (0.6-3.0 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human Activin B beta B subunit in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) Inhibin B or rhActivin A is observed. In Western Blots, approximately 20% cross-reactivity with rhInhibin B is observed and no cross‑reactivity with rhActivin A or recombinant mouse Activin A is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.