Activin A (beta A subunit) Antibody - CD BioSciences

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Activin A (beta A subunit) Antibody

Activin A (beta A subunit) Antibody

SPA-06013

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25 µg Online Inquiry
100 µg Online Inquiry
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Target Information
Target Name Inhibin
Gene Abbr. INHBA
Gene ID 3624
Full Name inhibin subunit beta A
Alias EDF, FRP
Introduction Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin and Inhibin are produced as precursor proteins. Their amino terminal propeptides are proteolytically cleaved and facilitate formation of disulfide-linked dimers of the bioactive proteins. Activins are nonglycosylated homodimers or heterodimers of various beta subunits ( beta A, beta B, beta C, and beta E in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two beta A chains. The beta A subunit can also heterodimerize with a beta B or beta C subunit to form Activin AB and Activin AC, respectively.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Chinese hamster ovary cell line CHO-derived recombinant human Activin A.
Usage
Application WB, IHC, IF
Dilutions Western Blot (0.1 µg/mL); Immunohistochemistry (5-15 µg/mL); Immunofluorescence (5-25 µg/mL); Neutralization (2-6 µg/mL)
Reactivity Human, Mouse, Rat
Specificity Detects human, mouse and rat Activin A in direct ELISAs and Western Blots.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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