Abexinostat (PCI-24781) - CD BioSciences

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Abexinostat (PCI-24781)

Abexinostat (PCI-24781)

SPC-00091

Abexinostat (PCI-24781)

CAS No. 783355-60-2

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10 mM (1 mL in DMSO) Online Inquiry
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HDAC inhibitor

Description
Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Product Details
CAS No. CAS No. 783355-60-2
Description Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Formula C21H23N3O5
Molecular Weight 397.42
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms CRA-024781
SMILES CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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