Cat#: CCR-0218
Propargyl-PEG6-acid, ≥95%
Synonyms (s): 4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, Propargyl-PEG6-CH2CO2H
Empirical Formula (Hill Notation): C16H28O8
Size: 250 mg; 1 g
Product Introduction
Molecular Weight | 348.39 |
NACRES | NA.22 |
CAS Number | 1951438-84-8 |
MDL Number | MFCD28950778 |
Assay | ≥95% |
Form | Liquid |
Reaction Suitability | Reaction type: click chemistry |
Smiles String | OC(CCOCCOCCOCCOCCOCCOCC#C)=O |
Storage Temp. | -20 °C |
Application
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Safety Information
Storage Class Code | 12 - Non Combustible Liquids |
WGK | WGK 3 |
For research use only. Not for clinical use.