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Oral Drug Delivery System Development Service

Oral Drug Delivery System Development Service

Dendrimers have been extensively studied for oral drug delivery due to their unique properties such as high-water solubility, uniform size, and ability to carry a large number of drug molecules per dendrimer molecule. CD BioSciences has a long-standing commitment to the development of novel dendrimer macromolecules. Our dedicated scientists are committed to helping our customers design and prepare dendrimer systems for oral delivery. We are pleased to leverage our extensive experience and advanced platform to provide the best possible service to meet our customers' every need.


Introduction into Oral Drug Delivery System

Oral drug delivery systems are methods of administering medications through the mouth and digestive system. These systems are the most used method of drug delivery, as they are convenient and easy to use. Oral drug delivery systems are preferred for their convenience, low cost, and ease of administration. Oral drug delivery systems include:

  • Tablets and Capsules
  • Controlled-release Formulations
  • Buccal and Sublingual Formulations
  • Liquid Formulations
  • Chewable Tablets
  • Enteric-coated Formulations

Development of Dendrimers for Oral Drug Delivery

Development of Dendrimers for Oral Drug Delivery

Dendrimers are highly branched, synthetic macromolecules with a well-defined structure and a high degree of surface functionality. These unique properties make them attractive candidates for drug delivery systems. Dendrimers can be designed to enhance drug solubility, bioavailability, stability, and target specificity. In terms of oral drug delivery, dendrimers offer several advantages over traditional drug delivery systems. For example, they can protect drugs from degradation in the gastrointestinal tract and improve their absorption by increasing their residence time in the intestinal lumen. They can also help to overcome the limitations of poorly soluble drugs by increasing their solubility and bioavailability. Additionally, dendrimers can be functionalized with ligands that target specific cells or tissues, enabling them to deliver drugs directly to their intended site of action. This can help to minimize the side effects of drugs and increase their therapeutic efficacy.

The process of developing dendrimers for oral drug delivery typically involves several steps:

  • Design and Synthesis
  • Drug Loading
  • In vitro and in vivo Evaluation
  • Characterization
  • Stability Testing
  • Optimization

Challenges in Developing Denderimers for Oral Drug Delivery

In recent years, there has been growing interest in the development of dendrimers for oral drug delivery. However, there are several challenges that must be overcome in order to make this approach effective.

  • Maintaining Stability in the Gastrointestinal Environment
    One major challenge is the stability of dendrimers in the harsh environment of the gastrointestinal tract. Dendrimers can be broken down by enzymes in the gut, reducing their effectiveness as drug delivery vehicles.
  • Reducing Potential Toxicity
    Another challenge in oral drug delivery using dendrimers is their potential toxicity.

Our Services

As an industry leader specializing in the development of dendrimer products, CD BioSciences has accumulated extensive experience in the development of novel dendrimer systems for oral drug delivery. Our dedicated scientists specialize in organic chemistry, materials science and pharmacology and would be happy to help you solve the difficulties in developing dendrimers for oral administration. Our services include improving the stability of dendrimers in the gastrointestinal tract (reducing enzymatic degradation) and reducing cytotoxicity. We are confident that we can meet each of your specific needs.

Why Choose Us?

  • Multiple dendrimer engineering services
  • Professional knowledge and advanced technology platform
  • Experienced and expert level scientists
  • Innovative products and high-quality, hassle-free, cost-effective services
  • Fast turnaround time

Want to Learn More?

CD BioSciences has a world-leading technology platform and dedicated scientific staff, making us a leading service provider focused on dendrimer product development. At CD BioSciences, we have innovative dendrimer products and are committed to meeting the unique needs of our customers in each of their dendrimer application projects by providing customized services. If you are interested in our services or have any additional questions, please feel free to contact us.

For research use only. Not for clinical use.