Cat#: CCR-0174
17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid
Synonyms (s): Azido-PEG5-CH2CO2H, Azido-PEG5-acid, N3-PEG5-CH2COOH
Empirical Formula (Hill Notation): C12H23N3O7
Size: 100 mg
Product Introduction
Molecular Weight | 321.33 |
CAS Number | 217180-81-9 |
MDL Number | MFCD31561141 |
Assay | ≥95% |
Form | (Liquid or Semi-solid or Paste or Solid) |
Reaction Suitability | Reaction type: click chemistry |
Smiles String | OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O |
Storage Temp. | 2-8 °C |
Application
This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Safety Information
Storage Class Code | 10 - Combustible liquids |
WGK | WGK 3 |
For research use only. Not for clinical use.