2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

Synonyms (s): Carboxyl diazirine alkyne, Probe building block

Empirical Formula (Hill Notation): C₁₂H₇F₃N₂O₃

Size: 25 mg

Product Introduction

Molecular Weight	284.19
CAS Number	2187374-12-3
Assay	≥95%
Form	Powder
Reaction Suitability	Reaction type: click chemistry
Smiles String	C#CCOC1=CC(C2(N=N2)C(F)(F)F)=CC=C1C(O)=O
Storage Temp.	-20 °C

Application

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Safety Information

Storage Class Code	13 - Non Combustible Solids
WGK	WGK 3

For research use only. Not for clinical use.