Cat#: CLP-0131
t-Boc-N-amido-PEG1-CH2CO2H
Empirical Formula (Hill Notation): C9H17NO5
Size: 50 mg
Product Introduction
Molecular Weight | 219.23 |
NACRES | NA.22 |
CAS Number | 142929-49-5 |
MDL Number | MFCD09909935 |
Form | Solid or Viscous liquid |
Reaction Suitability | Reagent type: Cross-linking reagent |
Smiles String | O=C(O)COCCNC(OC(C)(C)C)=O |
Storage Temp. | -20 °C |
Application
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains a single PEG unit to help improve solubility
t-Boc-N-amido-PEG1-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG1-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Safety Information
Storage Class Code | 12 - Non Combustible Liquids |
WGK | WGK 3 |
For research use only. Not for clinical use.