KB05yne

Synonyms (s): 4-(N-(4-Bromophenyl)acrylamido)-N-(hex-5-yn-1-yl)benzamide, Functionalized scout fragment

Empirical Formula (Hill Notation): C₂₂H₂₁BrN₂O₂

Size: 10 mg

Product Introduction

Molecular Weight	425.32
Assay	≥95%
Form	Powder or Solid
Reaction Suitability	Reagent type: chemical modification; Reagent reaction type: click chemistry
Storage Temp.	2-8 °C

Application

KB02yne is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as "undruggable," or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Technology spotlight: Proteomic Ligandability Assessment

Safety Information

Storage Class Code	10 - Combustible liquids
WGK	WGK 3

For research use only. Not for clinical use.