(1R,4R,8R)-5-Benzyl-2-isobutyl-8-methoxy-1,8-dimethylbicyclo[2.2.2]octa-2,5-diene

Synonyms (s): (1R,4R,8R) Carreira DOLEFIN Ligand, (1R,4R,8R)-8-Methoxy-1,8-dimethyl-2-(2-methylpropyl)-5-(phenylmethyl)bicyclo[2.2.2]octa-2,5-diene

Empirical Formula (Hill Notation): C₂₂H₃₀O

Size: 100 mg

Product Introduction

Molecular Weight	310.47
CAS Number	948594-95-4
MDL Number	MFCD08702680
PubChem Substance ID	24885054
Assay	95%
Form	Liquid
Reaction Suitability	Reaction type: click chemistry
Smiles String	CO[C@]1(C)C[C@]2(C)C=C(Cc3ccccc3)[C@H]1C=C2CC(C)C
InChI	1S/C22H30O/c1-16(2)11-19-13-20-18(12-17-9-7-6-8-10-17)14-21(19,3)15-22(20,4)23-5/h6-10,13-14,16,20H,11-12,15H2,1-5H3/t20-,21+,22-/m1/s1
InChI key	ACWLDJOHMGJACE-BHIFYINESA-N

Application

Carreira DOLEFIN Ligands
(1R, 4R, 8R) Carreira DOLEFIN Ligand is a chiral diene ligand that can be used in: The asymmetric Rh-catalyzed arylation of alkenylheterocycles by conjugate additions with various aryl boronic acids. The enantioselective synthesis of 3,3-diarylpropanals by conjugate addition of aromatic boronic acids to cinnamaldehyde derivatives in the presence of a rhodium catalyst. The asymmetric synthesis of pyrrolizidinones by rhodium-catalyzed 1,4-addition of aryl boronic acids to pyrrolidine acceptor.

Safety Information

For research use only. Not for clinical use.