Lung Cancer Calu-6 Transfection Kit

Description

Calu-6 is a human lung cancer cell line that was originally isolated from the pleural effusion of a patient with an adenocarcinoma of the lung. This cell line is commonly used as a model system to study various aspects of lung cancer, including the molecular mechanisms underlying tumor growth and metastasis.

Calu-6 cells are characterized by their ability to grow as adherent monolayers and exhibit a number of features associated with cancer cells, such as anchorage-independent growth, increased invasiveness, and resistance to apoptosis. They have been extensively used to investigate the effects of various therapeutic agents, including chemotherapy and targeted therapies, on lung cancer cells.

Calu-6 cells have been found to express a number of molecular markers commonly associated with lung cancer, including EGFR, HER2, and MET, and thus have been used to study the effects of inhibitors and monoclonal antibodies targeting these receptors. They have also been used to investigate the role of specific signaling pathways, such as the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK pathways, in lung cancer cell proliferation and survival.

In order to facilitate in-depth research, a specific and efficient cell transfection system is essential. To this end, CD BioSciences has developed a specific transfection kit for the Calu-6 cell line.