Zinc finger CCCH domain-containing protein 19 (At2g16470), Recombinant Protein
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Zinc finger CCCH domain-containing protein 19 (At2g16470), Recombinant Protein

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Cat: RP09941
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Zinc finger CCCH domain-containing protein 19 (At2g16470) , partial
Product Gene Name
At2g16470 recombinant protein
Product Synonym Gene Name
At2g16470
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
195,051 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_179241.4
NCBI GI #
240254462
NCBI GenBank Nucleotide #
NM_127202.5
NCBI GeneID
816147
NCBI Official Full Name
GW repeat- and PHD finger-containing protein NERD
NCBI Official Symbol
NERD
NCBI Official Synonym Symbols
F16F14.1; F16F14_1; Needed for RDR2-independent DNA methylation
NCBI Protein Information
GW repeat- and PHD finger-containing protein NERD
NCBI Summary
Encodes NERD (Needed for RDR2-independent DNA methylation), a plant-specific GW repeat- and PHD finger-containing protein involved in siRNA-dependent DNA methylation.
UniProt Gene Name
NERD
UniProt Synonym Gene Names
AtC3H19
UniProt Protein Name
Zinc finger CCCH domain-containing protein 19
UniProt Synonym Protein Names
Protein Needed for RDR2-independent DNA methylation
UniProt Primary Accession #
Q9SIV5
UniProt Secondary Accession #
Q8S8E0; Q9SIV4; F4IKD7
UniProt Related Accession #
Q9SIV5
UniProt Comments
Plays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1, RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci.

For research use only, not for clinical use.