NCBI Accession #
NP_001319473.1
NCBI GenBank Nucleotide #
NM_001337544.1
NCBI Official Full Name
zeta-carotene desaturase
NCBI Official Synonym Symbols
PDE181; PIGMENT DEFECTIVE EMBRYO 181; PRE ZETA-CAROTENE DESATURASE PRECURSOR; SPC1; SPONTANEOUS CELL DEATH 1; T9J14.18; zeta-carotene desaturase
NCBI Protein Information
zeta-carotene desaturase
NCBI Summary
Involved in the biosynthesis of carotenes and xanthophylls, reduces zeta-carotene to lycopene.
UniProt Protein Name
Zeta-carotene desaturase, chloroplastic/chromoplastic
UniProt Synonym Protein Names
9,9'-di-cis-zeta-carotene desaturase
UniProt Primary Accession #
Q38893
UniProt Secondary Accession #
Q8LD88; Q93YN2; Q9CAV3; Q9LLY1; A0A1I9LPJ6
UniProt Related Accession #
Q38893
UniProt Comments
Plays a crucial role in plant growth and development. Is essential for the biosynthesis of carotenoids. Carotenoids are involved in different physiological processes, including coloration, photoprotection, biosynthesis of abscisic acid (ABA) and chloroplast biogenesis (PubMed:17468780, PubMed:24907342). Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'. Shows stereoselectivity toward trans C15-C15'zeta-carotene double bond. The zeta-carotene produced by the phytoene desaturase PDS has a C15-C15' double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS. The main product is 7,9,7',9'-tetra-cis-lycopene (pro-lycopene) (PubMed:9914519).