NCBI Accession #
NP_200432.1
NCBI GenBank Nucleotide #
NM_125004.3
NCBI Official Full Name
WPP domain interacting protein 2
NCBI Official Symbol
WIP2
NCBI Official Synonym Symbols
K24C1.2; K24C1_2; WPP domain interacting protein 2
NCBI Protein Information
WPP domain interacting protein 2
NCBI Summary
Encodes an outer nuclear membrane protein that anchors RanGAP1 to the nuclear envelope. It interacts with SUN proteins and is required for maintaining the elongated nuclear shape of epidermal cells.
UniProt Protein Name
WPP domain-interacting protein 2
UniProt Primary Accession #
Q9FH18
UniProt Secondary Accession #
Q5XUY7; Q5XUY8
UniProt Related Accession #
Q9FH18
UniProt Comments
Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303).