NCBI Accession #
NP_001154269.1
NCBI GenBank Nucleotide #
NM_001160797.2
NCBI Official Full Name
WPP domain interacting protein 1
NCBI Official Symbol
WIP1
NCBI Official Synonym Symbols
Arabidopsis thaliana WPP domain interacting protein 1; AtWIP1; WPP domain interacting protein 1
NCBI Protein Information
WPP domain interacting protein 1
NCBI Summary
Encodes an outer nuclear membrane protein that anchors RanGAP1 to the nuclear envelope. It interacts with SUN proteins and is required for maintaining the elongated nuclear shape of epidermal cells.
UniProt Protein Name
WPP domain-interacting protein 1
UniProt Primary Accession #
Q8GXA4
UniProt Secondary Accession #
O65589
UniProt Related Accession #
Q8GXA4
UniProt Comments
Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715, PubMed:18591351). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303).