NCBI Accession #
NP_186777.1
NCBI GenBank Nucleotide #
NM_110994.3
NCBI Official Full Name
voltage dependent anion channel 1
NCBI Official Symbol
VDAC1
NCBI Official Synonym Symbols
5076; ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1; ATVDAC1; T22N4.9; T22N4_9; VDAC1; voltage dependent anion channel 1
NCBI Protein Information
voltage dependent anion channel 1
NCBI Summary
Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
UniProt Synonym Gene Names
AtVDAC1; VDAC-1
UniProt Protein Name
Mitochondrial outer membrane protein porin 1
UniProt Synonym Protein Names
Voltage-dependent anion-selective channel protein 1; AtVDAC1; VDAC-1
UniProt Entry Name
VDAC1_ARATH
UniProt Related Accession #
Q9SRH5
UniProt Comments
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective . Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.