NCBI Accession #
NP_001319779.1
NCBI GenBank Nucleotide #
NM_001339858.1
NCBI Official Full Name
villin 3
NCBI Official Symbol
VLN3
NCBI Official Synonym Symbols
ATVLN3; F28O9.1; villin 3
NCBI Protein Information
villin 3
NCBI Summary
Encodes a protein with high homology to animal villin. VLN3 is a Ca2+-regulated villin involved in actin filament bundling.
UniProt Protein Name
Villin-3
UniProt Primary Accession #
O81645
UniProt Secondary Accession #
Q9LEA4; Q9SCN1; A0A1I9LLW4; C0Z212
UniProt Related Accession #
O81645
UniProt Comments
Binds actin and actin filament bundles in a Ca2+-insensitive manner, but severs actin filaments in a calcium-dependent manner, regardless of the presence or not of VLN1 (AC O81643). Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles, to regulate directional organ growth (PubMed:22209875) and in sclerenchyma development (PubMed:22563899).