NCBI Accession #
NP_182039.1
NCBI GenBank Nucleotide #
NM_130077.3
NCBI Official Full Name
plant VAP homolog 12
NCBI Official Symbol
PVA12
NCBI Official Synonym Symbols
plant VAP homolog 12; T14P1.5
NCBI Protein Information
plant VAP homolog 12
NCBI Summary
Encodes a Plant VAMP-Associated protein that localizes to the ER and binds to the sitosterol-binding protein ORP3a. The WFDE motif in ORP3a appears to be important for this direct interaction. Mutation of this motif causes ORP3a to relocalize to the Golgi and cytosol. The interaction between PVA12 and ORP3a does not appear to be sterol-dependent.
UniProt Synonym Gene Names
VAP12; AtPVA12
UniProt Protein Name
Vesicle-associated protein 1-2
UniProt Synonym Protein Names
Plant VAP homolog 12; AtPVA12
UniProt Primary Accession #
Q9SHC8
UniProt Related Accession #
Q9SHC8
UniProt Comments
Vesicle-associated protein that binds the oxysterol-binding protein ORP3A and allows its targeting to the ER.