NCBI Accession #
NP_181352.1
NCBI GenBank Nucleotide #
NM_129373.4
NCBI Official Full Name
cation exchanger 1
NCBI Official Symbol
CAX1
NCBI Official Synonym Symbols
ATCAX1; cation exchanger 1; F16M14.10; F16M14_10; HIGH AFFINITY CALCIUM ANTIPORTER CAX1; RARE COLD INDUCIBLE 4; RCI4
NCBI Protein Information
cation exchanger 1
NCBI Summary
Encodes a high affinity vacuolar calcium antiporter. The residue His 338 is critical to Ca2+ transport activity. Disruption of CAX1 reduces manganese and zinc of shoot tissue and results in a decrease in the activity of vacuolar V-type proton ATPase.
UniProt Synonym Gene Names
RCI4
UniProt Protein Name
Vacuolar cation/proton exchanger 1
UniProt Synonym Protein Names
Ca(2+)/H(+) antiporter CAX1; Ca(2+)/H(+) exchanger 1; Protein CATION EXCHANGER 1; Protein RARE COLD INDUCIBLE 4
UniProt Primary Accession #
Q39253
UniProt Secondary Accession #
O80442; Q56WC8
UniProt Related Accession #
Q39253
UniProt Comments
Vacuolar cation/proton exchanger (CAX). Translocates Ca2+ and other metal ions into vacuoles using the proton gradient formed by H+-ATPase and H+-pyrophosphatase. Involved in ion homeostasis in association with CAX3. May play a role in cold-acclimation response.