NCBI Accession #
NP_181910.1
NCBI GenBank Nucleotide #
NM_129944.3
NCBI Official Full Name
UDP-glucosyltransferase 74F2
NCBI Official Symbol
UGT74F2
NCBI Official Synonym Symbols
Arabidopsis thaliana salicylic acid glucosyltransferase 1; ATSAGT1; F18O19.7; GT; SAGT1; salicylic acid glucosyltransferase 1; SGT1; UDP-glucose:salicylic acid glucosyltransferase 1; UDP-glucosyltransferase 74F2
NCBI Protein Information
UDP-glucosyltransferase 74F2
NCBI Summary
Induced by Salicylic acid, virus, fungus and bacteria.Involved in the tryptophan synthesis pathway. Independent of NPR1 for their induction by salicylic acid. UGT74F1 transfers UDP:glucose to salicylic acid (forming a glucoside (SAG) and a glucose ester (SGE)), benzoic acid, and athranilate in vitro. UGT74F2 shows a weak ability to catalyze the formation of the p-aminobenzoate-glucose ester in vitro. But, UGT75B1 appears to be the dominant pABA acylglucosyltransferase in vivo based on assays in leaves, flowers, and siliques. The true biological substrate(s) of UGT74F2 are not known, but mutant plants lacking UGT74F2 have a decreased level of SAG and SGE.
UniProt Gene Name
UGT74F2
UniProt Synonym Gene Names
GT; SAGT1; SGT1
UniProt Protein Name
UDP-glycosyltransferase 74F2
UniProt Synonym Protein Names
AtSGT1; Salicylic acid glucosyltransferase 1
UniProt Primary Accession #
O22822
UniProt Comments
Glycosyltransferase that glucosylates benzoic acid and derivatives. Substrate preference is benzoic acid > salicylic acid (SA) > 3-hydroxybenzoic acid > 4-hydroxybenzoic acid. Catalyzes the formation of both SA 2-O-beta-D-glucoside (SAG) and SA glucose ester (SGE). Has high affinity for the tryptophan precursor anthranilate. Catalyzes the formation of anthranilate glucose ester. Is the major source of this activity in the plant.