NCBI Accession #
NP_197069.1
NCBI GenBank Nucleotide #
NM_121569.3
NCBI Official Full Name
reversibly glycosylated polypeptide 2
NCBI Official Symbol
RGP2
NCBI Official Synonym Symbols
ATRGP2; F14F8.30; F14F8_30; reversibly glycosylated polypeptide 2; REVERSIBLY GLYCOSYLATED POLYPEPTIDE 2
NCBI Protein Information
reversibly glycosylated polypeptide 2
NCBI Summary
RGP2 is a UDP-arabinose mutase that catalyzes the interconversion between the pyranose and furanose forms of UDP-L-arabinose. It appears to be required for proper cell wall formation. rgp1(at3g02230)/rgp2 double mutants have a male gametophyte lethal phenotype. RGP2 fusion proteins can be found in the cytosol and peripherally associated with the Golgi apparatus. RGP2 was originally identified as Reversibly Glycosylated Polypeptide-2. Constitutive expression in tobacco impairs plant development and virus spread.
UniProt Synonym Gene Names
AtRGP2
UniProt Protein Name
UDP-arabinopyranose mutase 2
UniProt Synonym Protein Names
Reversibly glycosylated polypeptide 2
UniProt Primary Accession #
Q9LFW1
UniProt Secondary Accession #
O22428; Q8LB19
UniProt Related Accession #
Q9LFW1
UniProt Comments
UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc) (PubMed:21478444). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Probably involved in the formation of the pectocellulosic cell wall layer intine. Is probably active as heteromer in vivo (PubMed:17071651).