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Ubiquitin-like-specific protease 1D (ULP1D), Recombinant Protein
Cat: RP05469
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Ubiquitin-like-specific protease 1D (ULP1D) , partial
Product Gene Name
ULP1D recombinant protein
Product Synonym Gene Name
ULP1D
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
67,191 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Ubiquitin-like-specific protease
NCBI/Uniprot Data
NCBI Accession #
NP_176228.3
NCBI GI #
145336892
NCBI GenBank Nucleotide #
NM_104712.5
NCBI GeneID
842317
NCBI Official Full Name
UB-like protease 1D
NCBI Official Symbol
ULP1D
NCBI Official Synonym Symbols
OTS1; OVERLY TOLERANT TO SALT 1; T13D8.11; T13D8_11; UB-like protease 1D
NCBI Protein Information
UB-like protease 1D
NCBI Summary
Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. sGFP:OTS1 protein accumulates in the nucleus. Double mutant analysis with ULP1C/OTS2 indicates that these genes are involved in salt stress responses and flowering time regulation. Over-expression of 35S:OTS1 increases salt tolerance and reduces the level of SUMO-conjugated proteins. OTS1 transcript levels do not appear to change in response to salt, but, salt stress reduces the level of OTS1 protein in a proteasome-dependent manner.
UniProt Gene Name
ULP1D
UniProt Synonym Gene Names
OTS1
UniProt Protein Name
Ubiquitin-like-specific protease 1D
UniProt Synonym Protein Names
Protein OVERLY TOLERANT TO SALT 1
UniProt Primary Accession #
Q2PS26
UniProt Secondary Accession #
O80745
UniProt Related Accession #
Q2PS26
UniProt Comments
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5. Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3. Protease activity mainly directed at deconjugating SUM1 and SUM2 from their target proteins. Regulates salt stress responses and flowering time. Redundant with ULP1C.
For research use only, not for clinical use.