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Ubiquitin-like modifier-activating enzyme atg7 (ATG7), Recombinant Protein
Cat: RP02488
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Ubiquitin-like modifier-activating enzyme atg7 (ATG7) , partial
Product Gene Name
ATG7 recombinant protein
Product Synonym Gene Name
ATG7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
76,522 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Ubiquitin-like modifier-activating enzyme
NCBI/Uniprot Data
NCBI Accession #
NP_568652.1
NCBI GI #
18422607
NCBI GenBank Nucleotide #
NM_123958.3
NCBI GeneID
834630
NCBI Official Full Name
ThiF family protein
NCBI Official Symbol
APG7
NCBI Official Synonym Symbols
ATAPG7; ATATG7; ATG7; AUTOPHAGY 7; AUTOPHAGY-RELATED 7; K15I22.10; K15I22_10; PEROXISOME UNUSUAL POSITIONING 4; PEUP4
NCBI Protein Information
ThiF family protein
NCBI Summary
Component of autophagy conjugation pathway. Required for proper senescence. Contributes to plant basal immunity towards fungal infection.
UniProt Gene Name
ATG7
UniProt Synonym Gene Names
; AtAPG7
UniProt Protein Name
Ubiquitin-like modifier-activating enzyme atg7
UniProt Synonym Protein Names
ATG12-activating enzyme E1 atg7; Autophagy-related protein 7; AtAPG7; Protein PEROXISOME UNUSUAL POSITIONING 4
UniProt Primary Accession #
Q94CD5
UniProt Secondary Accession #
Q9FJ46
UniProt Related Accession #
Q94CD5
UniProt Comments
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process (PubMed:12070171). Involved in the degradation of damaged peroxisomes (PubMed:24368788). Involved in the non-selective degradation of chlorophylls and photosynthetic proteins during stress-induced leaf yellowing (PubMed:24510943).
For research use only, not for clinical use.