NCBI Accession #
NP_001078272.1
NCBI GenBank Nucleotide #
NM_001084803.1
NCBI Official Full Name
ubiquitin E2 variant 1D-4
NCBI Official Symbol
UEV1D-4
NCBI Official Synonym Symbols
F3C22.2; MMS2 ZWEI HOMOLOGUE 4; MMZ4; UBIQUITIN E2 VARIANT 1D; ubiquitin E2 variant 1D-4; UEV1D
NCBI Protein Information
ubiquitin E2 variant 1D-4
UniProt Synonym Gene Names
MMZ4; Ubc enzyme variant 1D
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 variant 1D
UniProt Synonym Protein Names
Protein MMS ZWEI HOMOLOG 4
UniProt Primary Accession #
Q9SVD7
UniProt Secondary Accession #
Q3EAL0; A8MSC0
UniProt Related Accession #
Q9SVD7
UniProt Comments
Has no ubiquitin ligase activity on its own. The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. May play a role in the control of progress through the cell cycle and differentiation. Involved in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.