Ubiquitin-40S ribosomal protein S27a-1 (RPS27AA), Recombinant Protein

Full Product Name

Recombinant Arabidopsis thaliana Ubiquitin-40S ribosomal protein S27a-1 (RPS27AA)

Product Gene Name

RPS27AA recombinant protein

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Sequence

MQIFVKTLTG KTITLEVESS DTIDNVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLADYN IQKESTLHLV LRLRGG

Sequence Positions

1-76, Full length protein

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

17,672 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Ubiquitin-40S ribosomal protein

NCBI Accession #

NP_173755.1

NCBI GI #

15220742

NCBI GenBank Nucleotide #

NM_102190.3

NCBI GeneID

838949

NCBI Official Full Name

Ribosomal protein S27a / Ubiquitin family protein

NCBI Official Symbol

AT1G23410

NCBI Official Synonym Symbols

F26F24.28; F26F24_28

NCBI Protein Information

Ribosomal protein S27a / Ubiquitin family protein

UniProt Gene Name

RPS27AA

UniProt Synonym Gene Names

UBQ16

UniProt Protein Name

Ubiquitin-40S ribosomal protein S27a-1

UniProt Primary Accession #

P59271

UniProt Secondary Accession #

O80715; P59263; Q29PZ3; Q38875; Q9LDJ2; Q9LYW1; Q9M0W3; Q9M1P9; Q9S7X3

UniProt Related Accession #

P59271

UniProt Comments

Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling .