Type I inositol 1,4,5-trisphosphate 5-phosphatase CVP2 (CVP2), Recombinant Protein
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Type I inositol 1,4,5-trisphosphate 5-phosphatase CVP2 (CVP2), Recombinant Protein

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Cat: RP01830
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Type I inositol 1,4,5-trisphosphate 5-phosphatase CVP2 (CVP2) , partial
Product Gene Name
CVP2 recombinant protein
Product Synonym Gene Name
CVP2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
57,931 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_001322092.1
NCBI GI #
1063680525
NCBI GenBank Nucleotide #
NM_001331550.1
NCBI GeneID
837048
NCBI Official Full Name
DNAse I-like superfamily protein
NCBI Official Symbol
CVP2
NCBI Official Synonym Symbols
COTYLEDON VASCULAR PATTERN 2; T25N20.12; T25N20_12
NCBI Protein Information
DNAse I-like superfamily protein
NCBI Summary
Encodes an inositol polyphosphate 5' phosphatase (5PTase) that is required for the proper recruitment of cells into developing vascular tissue in leaves and cotyledons. It is most similar to Type I 5PTases that are known to cleave a phosphate from IP3 or IP4. cvp2 mutants have elevated levels of IP3 and are hypersensitive to ABA in seed germination assays.
UniProt Gene Name
IP5P6
UniProt Synonym Gene Names
; At5PTase6Curated
UniProt Protein Name
Type IV inositol polyphosphate 5-phosphatase 6
UniProt Synonym Protein Names
Protein COTYLEDON VASCULAR PATTERN 2
UniProt Primary Accession #
Q9LR47
UniProt Related Accession #
Q9LR47
UniProt Comments
Has phosphatase activity toward PtdIns(4,5)P2 and PtdIns(3,4,5)P3 (PubMed:19473324). Required for the patterning of procambium and during the differentiation of vascular tissues. Acts before the acquisition of preprocambial identity. Seems to be also involved in the abscisic acid (ABA) signaling pathway (PubMed:10559439, PubMed:15100402). Acts redundantly with CVL1 for maintaining vascular continuity (PubMed:19363154, PubMed:25813544). Regulates phosphoinositide-dependent VAN3 localization (PubMed:19473324).

For research use only, not for clinical use.