NCBI Accession #
NP_567547.1
NCBI GenBank Nucleotide #
NM_117911.4
NCBI Official Full Name
myo-inositol polyphosphate 5-phosphatase 2
NCBI Official Symbol
IP5PII
NCBI Official Synonym Symbols
4; 5)P3 5-PHOSPHATASE II; 5PTASE2; AT5PTASE2; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE II; INOSITOL(1; myo-inositol polyphosphate 5-phosphatase 2; T6K21.190; T6K21_190
NCBI Protein Information
myo-inositol polyphosphate 5-phosphatase 2
NCBI Summary
Encodes an inositol polyphosphate 5-phosphatase that appears to have Type I activity. It can dephosphorylate IP3(inositol(1,4,5)P3) and IP4 (inositol(1,3,4,5)P4), but it does not appear to be active against phosphatidylinositol 4,5 bisphosphate. Overexpression of this gene renders plants insensitive to ABA in germination and growth assays.
UniProt Synonym Gene Names
At5PTase2
UniProt Protein Name
Type I inositol polyphosphate 5-phosphatase 2
UniProt Primary Accession #
Q9FUR2
UniProt Secondary Accession #
O49700; Q9SNF1; Q9ZSC3
UniProt Related Accession #
Q9FUR2
UniProt Comments
Has phosphatase activity toward Ins(1,4,5)P3 and Ins(1,3,4,5)P4. Seems to be involved in the abscisic acid (ABA) signaling pathway (PubMed:11340187). Could also be able to hydrolyze PtdIns(4,5)P2 and PtdIns(3,4,5)P3 (PubMed:23658066).