NCBI Accession #
NP_180090.6
NCBI GenBank Nucleotide #
NM_128075.7
NCBI Official Full Name
response regulator 12
NCBI Official Symbol
RR12
NCBI Official Synonym Symbols
ARR12; AtARR12; F13D4.140; F13D4_140; response regulator 12
NCBI Protein Information
response regulator 12
NCBI Summary
Encodes an Arabidopsis response regulator (ARR) protein that acts in concert with other type-B ARRs in the cytokinin signaling pathway. Also involved in cytokinin-dependent inhibition of hypocotyl elongation and cytokinin-dependent greening and shooting in tissue culture.
UniProt Protein Name
Two-component response regulator ARR12
UniProt Primary Accession #
P62598
UniProt Secondary Accession #
F4IRL1
UniProt Related Accession #
P62598
UniProt Comments
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455).