tRNA-splicing endonuclease subunit Sen2-2 (SEN2), Recombinant Protein
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tRNA-splicing endonuclease subunit Sen2-2 (SEN2), Recombinant Protein

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Cat: RP02453
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana tRNA-splicing endonuclease subunit Sen2-2 (SEN2)
Product Gene Name
SEN2 recombinant protein
Product Synonym Gene Name
SEN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAPRWKWKGA EAKALAEPIS KSVSELQLSL AETESSGTLS SCNVLLAVEP EQAELLDRCC FGRLVLSAEK IKKWIQLSFE EAFFLHYNLK CIKISLQGRC LENEVDTWLY MKSKRPNFPM FFKAYSHLRS KNWVLRSGLQ YGVDFVAYRH HPSLVHSEYS VLVQSGDSDR LRVWSDIHCA VRLSGSVAKT LLTLYVNGNF KGEDVNLLVC LENFTVEEQT ISRWSPELSR EDQSTNSKQH VPNVSNLNTL
Sequence Positions
1-250, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
28,519 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
tRNA-splicing endonuclease

NCBI/Uniprot Data

NCBI Accession #
NP_200831.1
NCBI GI #
15238643
NCBI GenBank Nucleotide #
NM_125416.4
NCBI GeneID
836145
NCBI Official Full Name
splicing endonuclease 2
NCBI Official Symbol
SEN2
NCBI Official Synonym Symbols
ATSEN2; F15L12.18; F15L12_18; splicing endonuclease 2; SPLICING ENDONUCLEASE 2
NCBI Protein Information
splicing endonuclease 2
NCBI Summary
putative subunit of tRNA splicing endonuclease
UniProt Gene Name
SEN2
UniProt Synonym Gene Names
AtSen2
UniProt Protein Name
tRNA-splicing endonuclease subunit Sen2-2
UniProt Synonym Protein Names
tRNA-intron endonuclease Sen2-2; AtSen2
UniProt Primary Accession #
Q9LSS3
UniProt Secondary Accession #
Q3E887
UniProt Related Accession #
Q9LSS3
UniProt Comments
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Probably carries the active site for 5'-splice site cleavage .

For research use only, not for clinical use.