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Transcriptional corepressor LEUNIG (LUG), Recombinant Protein
Cat: RP00522
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Transcriptional corepressor LEUNIG (LUG) , partial
Product Gene Name
LUG recombinant protein
Product Synonym Gene Name
LUG
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
102,233 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Transcriptional corepressor
NCBI/Uniprot Data
NCBI Accession #
NP_567896.1
NCBI GI #
18418034
NCBI GenBank Nucleotide #
NM_119407.3
NCBI GeneID
829390
NCBI Official Full Name
transcriptional corepressor LEUNIG
NCBI Official Symbol
LUG
NCBI Official Synonym Symbols
L23H3.30; L23H3_30; LEUNIG; RON2; ROTUNDA 2
NCBI Protein Information
transcriptional corepressor LEUNIG
NCBI Summary
LEUNIG regulates floral organ identity,gynoecium and ovule development. Negatively regulates AGAMOUS . Encodes a glutamine-rich protein with seven WD repeats similar to transcriptional corepressors.
UniProt Gene Name
LUG
UniProt Protein Name
Transcriptional corepressor LEUNIG
UniProt Synonym Protein Names
Protein ROTUNDA2
UniProt Primary Accession #
Q9FUY2
UniProt Secondary Accession #
Q9SZY9
UniProt Related Accession #
Q9FUY2
UniProt Comments
Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development (PubMed:11782418, PubMed:15277686, PubMed:7743940). Implicated in embryo and floral development (PubMed:18390806). Involved in post-synthesis cell wall modifications necessary for mucilage extrusion from seeds upon imbibition, probably by promoting the expression of genes required for mucilage maturation (PubMed:21362134, PubMed:21402796). Involved in vegetative leaf morphogenesis at later stages of leaf development by restricting cell expansion during leaf growth (PubMed:15208345). Regulates the maintenance on leaf polarity and meristem activity as well as the initiation of embryonic shoot apical meristem (SAM) development (PubMed:19837869).
For research use only, not for clinical use.