NCBI Accession #
NP_568334.1
NCBI GenBank Nucleotide #
NM_121662.3
NCBI Official Full Name
Homeodomain-like superfamily protein
NCBI Official Synonym Symbols
KAN1; KANADI; KANADI 1; MQK4.31; MQK4_31
NCBI Protein Information
Homeodomain-like superfamily protein
NCBI Summary
Encodes a KANADI protein (KAN) that regulates organ polarity in Arabidopsis. KAN is required for abaxial identity in both leaves and carpels, and encodes a nuclear-localized protein in the GARP family of putative transcription factors. Together with KAN2, this gene appears to be involved in the development of the carpel and the outer integument of the ovule.Along with KAN2 and KAN4, KAN1 appears to be required for proper regulation of PIN1 in early embryogenesis.
UniProt Synonym Gene Names
KAN
UniProt Protein Name
Transcription repressor KAN1
UniProt Synonym Protein Names
Protein KANADI 1
UniProt Primary Accession #
Q93WJ9
UniProt Secondary Accession #
Q94C09; Q9FFC8
UniProt Related Accession #
Q93WJ9
UniProt Comments
Transcriptional repressor that regulates lateral organ polarity. Promotes lateral organ abaxial identity by repressing the adaxial regulator ASYMMETRIC LEAVES2 (AS2) in abaxial cells. Required for abaxial identity in both leaves and carpels. Functions with KAN2 in the specification of polarity of the ovule outer integument. Regulates cambium activity by repressing the auxin efflux carrier PIN1. Plays a role in lateral root formation and development.