NCBI Accession #
NP_174541.1
NCBI GenBank Nucleotide #
NM_102998.4
NCBI Official Full Name
Basic helix-loop-helix (bHLH) DNA-binding family protein
NCBI Official Symbol
MYC2
NCBI Official Synonym Symbols
ATMYC2; F6N18.4; F6N18_4; JAI1; JASMONATE INSENSITIVE 1; JIN1; RD22BP1; ZBF1
NCBI Protein Information
Basic helix-loop-helix (bHLH) DNA-binding family protein
NCBI Summary
Encodes a MYC-related transcriptional activator with a typical DNA binding domain of a basic helix-loop-helix leucine zipper motif. Binds to an extended G-Box promoter motif and interacts with Jasmonate ZIM-domain proteins. Its transcription is induced by dehydration stress and ABA treatment. Negative regulator of blue light#Aeimediated photomorphogenic growth and blue and far-red-light#Aeiregulated gene expression. Positive regulator of lateral root formation. Regulates diverse JA-dependent functions. Negatively regulates Trp metabolism and biosynthesis of Trp-derived secondary metabolites. Positively regulates flavonoid biosynthesis, resistance to insects, and response to oxidative stress. Regulates other transcription factors, and negatively regulates its own expression.
UniProt Synonym Gene Names
BHLH6; EN38; JAI1; JIN1; RAP1; RD22BP1; ZBF1; AtMYC2; AtbHLH6; bHLH 6; RAP-1
UniProt Protein Name
Transcription factor MYC2
UniProt Synonym Protein Names
Basic helix-loop-helix protein 6; AtbHLH6; bHLH 6; Protein JASMONATE INSENSITIVE 1; R-homologous Arabidopsis protein 1; RAP-1; Transcription factor EN 38; Z-box binding factor 1 protein; bHLH transcription factor bHLH006; rd22BP1
UniProt Primary Accession #
Q39204
UniProt Secondary Accession #
O48644; Q5K1L7; Q8W2F4; Q9LPJ8
UniProt Related Accession #
Q39204
UniProt Comments
Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the promoters of the transcription factors PLETHORA1 (PLT1) and PLT2 and represses their expression. Negative regulator of blue light-mediated photomorphogenic growth and blue- and far-red-light regulated gene expression. Activates multiple TIFY/JAZ promoters. Positive regulator of lateral root formation. Regulates sesquiterpene biosynthesis. Subjected to proteasome-dependent proteolysis. The presence of the destruction element (DE) involved in turnover is required for the function to regulate gene transcription.