NCBI Accession #
NP_196791.1
NCBI GenBank Nucleotide #
NM_121290.3
NCBI Official Full Name
myb domain protein 46
NCBI Official Symbol
MYB46
NCBI Official Synonym Symbols
ATMYB46; myb domain protein 46; MYB DOMAIN PROTEIN 46; T24H18.40; T24H18_40
NCBI Protein Information
myb domain protein 46
NCBI Summary
Encodes MYB46, member of the R2R3 factor gene family. Modulates Disease Susceptibility to Botrytis cinerea.
UniProt Synonym Gene Names
AtMYB46
UniProt Protein Name
Transcription factor MYB46
UniProt Synonym Protein Names
Myb-related protein 46
UniProt Primary Accession #
Q9LXV2
UniProt Secondary Accession #
Q9ZTE1
UniProt Related Accession #
Q9LXV2
UniProt Comments
Transcription activator. Involved in the regulation of secondary wall biosynthesis in fibers and vessels (PubMed:17890373). Transcription activator of the mannan synthase CSLA9 that recognizes and binds to the DNA consensus sequence 5'-[AG][GT]T[AT]GGT[GA]-3' cis-regulatory element of CSLA9 promoter (PubMed:24243147). Transcription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1. Functions redundantly with MYB83 in the transcriptional regulatory cascade leading to secondary wall formation in fibers and vessels (PubMed:19808805). Transcription activator that binds to the DNA consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary wall MYB-responsive element (SMRE). Regulates directly numerous transcription factors and a number of genes involved in secondary wall biosynthesis that contain SMRE elements in their promoters (PubMed:22197883). Is an obligate component of the transcriptional regulatory complex toward the commitment of secondary wall cellulose synthesis. Is required for functional expression of the three secondary wall CESA genes, CESA4, CESA7 and CESA8 (PubMed:23726771).