NCBI Accession #
NP_563650.1
NCBI GenBank Nucleotide #
NM_100115.3
NCBI Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Official Symbol
HFR1
NCBI Official Synonym Symbols
FBI1; LONG HYPOCOTYL IN FAR-RED; REDUCED PHYTOCHROME SIGNALING 1; REDUCED SENSITIVITY TO FAR-RED LIGHT 1; REP1; RSF1; T6A9.4; T6A9_4
NCBI Protein Information
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Summary
Encodes a light-inducible, nuclear bHLH protein involved in phytochrome signaling. Mutants exhibit a long-hypocotyl phenotype only under far-red light but not under red light and are defective in other phytochrome A-related responses. Mutants also show blue light response defects. HFR1 interacts with COP1, co-localizes to the nuclear specks and is ubiquinated by COP1.
UniProt Synonym Gene Names
bHLH 26
UniProt Protein Name
Transcription factor HFR1
UniProt Synonym Protein Names
Basic helix-loop-helix protein 26
UniProt Primary Accession #
Q9FE22
UniProt Secondary Accession #
Q8GZ25; Q9FZ26
UniProt Related Accession #
Q9FE22
UniProt Comments
Atypical bHLH transcription factor that regulates photomorphogenesis through modulation of phytochrome (e.g. PHYA) and cryptochrome signalings (Ref. 4, PubMed:11090209, PubMed:10995393, PubMed:19482971). Suppresses the transcriptional regulation activity of PIF4 by forming non-DNA-binding heterodimer.