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Transcription factor FAMA (FMA), Recombinant Protein
Cat: RP00308
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Transcription factor FAMA (FMA)
Product Gene Name
FMA recombinant protein
Product Synonym Gene Name
FMA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDKDYSAPNF LGESSGGNDD NSSGMIDYMF NRNLQQQQKQ SMPQQQQHQL SPSGFGATPF DKMNFSDVMQ FADFGSKLAL NQTRNQDDQE TGIDPVYFLK FPVLNDKIED HNQTQHLMPS HQTSQEGGEC GGNIGNVFLE EKEDQDDDND NNSVQLRFIG GEEEDRENKN VTKKEVKSKR KRARTSKTSE EVESQRMTHI AVERNRRKQM NEHLRVLRSL MPGSYVQRGD QASIIGGAIE FVRELEQLLQ CLESQKRRRI LGETGRDMTT TTTSSSSPIT TVANQAQPLI ITGNVTELEG GGGLREETAE NKSCLADVEV KLLGFDAMIK ILSRRRPGQL IKTIAALEDL HLSILHTNIT TMEQTVLYSF NVKITSETRF TAEDIASSIQ QIFSFIHANT NISGSSNLGN IVFT
Sequence Positions
1-414, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
46,408 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_189056.2
NCBI GI #
30687365
NCBI GenBank Nucleotide #
NM_113319.5
NCBI GeneID
822000
NCBI Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Official Symbol
FMA
NCBI Official Synonym Symbols
FAMA
NCBI Protein Information
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Summary
Encodes a basic helix-loop-helix transcription factor whose activity is required to promote differentiation of stomatal guard cells and to halt proliferative divisions in their immediate precursors. It fulfills its role through recruitment of the Arabidopsis Retinoblastoma homologue, RETINOBLASTOMA-RELATED (RBR). Both transcript and protein are expressed in and are required for halting divisions at the end of the stomatal lineage. It also has a role in the promotion of guard cell fate and in controlling the transition from guard mother cell to guard cell. Its transcript levels change after inducing MUTE expression in a mute background.
UniProt Gene Name
FAMA
UniProt Synonym Gene Names
BHLH97; EN14; FMA; AtbHLH97; bHLH 97
UniProt Protein Name
Transcription factor FAMA
UniProt Synonym Protein Names
Basic helix-loop-helix protein 97; AtbHLH97; bHLH 97; Transcription factor EN 14; bHLH transcription factor bHLH097
UniProt Primary Accession #
Q56YJ8
UniProt Secondary Accession #
Q9LRN3
UniProt Related Accession #
Q56YJ8
UniProt Comments
Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956).
For research use only, not for clinical use.