NCBI Accession #
NP_191499.1
NCBI GenBank Nucleotide #
NM_115802.4
NCBI Official Full Name
protein GENOMES UNCOUPLED 4
NCBI Official Symbol
GUN4
NCBI Official Synonym Symbols
GENOMES UNCOUPLED 4
NCBI Protein Information
protein GENOMES UNCOUPLED 4
NCBI Summary
GUN, genomes uncoupled, is necessary for coupling the expression of some nuclear genes to the functional state of the chloroplast. Binds to the magnesium chelatase complex and promotes formation of the substrate,a tetrapyrrole signaling molecule. Porphyrin-binding protein that enhances the activity of Mg-chelatase. Although required for chlorophyll accumulation under normal growth conditions, GUN4 is not essential for chlorophyll synthesis.
UniProt Protein Name
Tetrapyrrole-binding protein, chloroplastic
UniProt Synonym Protein Names
Genomes uncoupled 4
UniProt Primary Accession #
Q9LX31
UniProt Secondary Accession #
Q8VZR4
UniProt Related Accession #
Q9LX31
UniProt Comments
Regulates chlorophyll synthesis and plastid-to-nucleus signal transduction by binding both the product and the substrate of Mg-chelatase, an enzyme that produces magnesium-protoporphyrin IX (Mg-Proto). Activates also Mg-chelatase. Neither binds abscisic acid (ABA) nor is involved in ABA signaling.