NCBI Accession #
NP_671769.1
NCBI GenBank Nucleotide #
NM_147236.3
NCBI Official Full Name
maternal effect embryo arrest 12
NCBI Official Symbol
MEE12
NCBI Official Synonym Symbols
maternal effect embryo arrest 12
NCBI Protein Information
maternal effect embryo arrest 12
UniProt Synonym Gene Names
TBP-associated factor 1B
UniProt Protein Name
TATA box-binding protein-associated factor RNA polymerase I subunit B
UniProt Synonym Protein Names
Central cell guidance protein; Protein MATERNAL EFFECT EMBRYO ARREST 12; TATA box-binding protein-associated factor 1B; TBP-associated factor 1B
UniProt Primary Accession #
Q5XVF0
UniProt Secondary Accession #
Q5XVE8; Q5XVE9
UniProt Related Accession #
Q5XVF0
UniProt Comments
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment . Required for the development of the one-cell zygote and endosperm in embryos (PubMed:15634699). Required for micropylar pollen tube guidance, but has no effect on ovule development and gametophytic cell fate specification (PubMed:18055609). May regulate the transcription of secreted cysteine-rich peptide (CRP) genes in the embryo sac (PubMed:26462908).