SUMO-activating enzyme subunit 1A (SAE1A), Recombinant Protein
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SUMO-activating enzyme subunit 1A (SAE1A), Recombinant Protein

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Cat: RP04723
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana SUMO-activating enzyme subunit 1A (SAE1A)
Product Gene Name
SAE1A recombinant protein
Product Synonym Gene Name
SAE1A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDGEELTEQE TALYDRQIRV WGANAQRRLT KAHILVSGIK GTVAEFCKNI VLAGVGSVTL MDDRLANMEA LNANFLIPPD ENVYSGKTVA EICSDSLKDF NPMVRVSVEK GDLSMLGTDF FEQFDVVVIG YGSRATKKYV NEKCRKLKKR VAFYTVDCRD SCGEIFVDLQ DYKYTKKKLE EMVECELNFP SFQEAISVPW KPIPRRTAKL YFAMRVIEVF EESEGRKHGE CSLLDLARVL EIKKQLCEAN SVSESHIPDI LLERLITGTT EFPPVCAIVG GILAQEVIKA VSGKGDPLKN FFYYDGEDGK GVMEDISDSF TS
Sequence Positions
1-322, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
36,123 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
SUMO-activating enzyme

NCBI/Uniprot Data

NCBI Accession #
NP_567712.1
NCBI GI #
18416454
NCBI GenBank Nucleotide #
NM_118626.3
NCBI GeneID
828596
NCBI Official Full Name
SUMO-activating enzyme 1A
NCBI Official Symbol
SAE1A
NCBI Official Synonym Symbols
AT-SAE1-1; ATSAE1A; F13M23.80; F13M23_80; SUMO-activating enzyme 1A; SUMO-ACTIVATING ENZYME 1A
NCBI Protein Information
SUMO-activating enzyme 1A
NCBI Summary
Encodes one of the two subunits of the SUMO activation enzyme required during sumolation. Sumolation is a post-translational protein modification process similar to ubiquitination during which a polypeptide (SUMO) is covalently attached to a target protein.
UniProt Gene Name
SAE1A
UniProt Synonym Gene Names
SAE1-1
UniProt Protein Name
SUMO-activating enzyme subunit 1A
UniProt Synonym Protein Names
SUMO-activating enzyme subunit 1-1; Ubiquitin-like 1-activating enzyme E1A
UniProt Primary Accession #
Q8VY78
UniProt Secondary Accession #
Q9SW32
UniProt Related Accession #
Q8VY78
UniProt Comments
The dimeric enzyme acts as an E1 ligase for SUMO1 and SUMO2. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Functionally redundant with its paralog SAE1B.

For research use only, not for clinical use.