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Squalene synthase (SQS1), Recombinant Protein
Cat: RP00376
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Squalene synthase (SQS1)
Product Synonym Names
Recombinant Squalene synthase (SQS1); Squalene synthase; SQS; SS EC= 2.5.1.21; FPP:FPP farnesyltransferase Farnesyl-diphosphate farnesyltransferase
Product Gene Name
SQS1 recombinant protein
Product Synonym Gene Name
SQS1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MGSLGTMLRY PDDIYPLLKM KRAIEKAEKQ IPPEPHWGFC YSMLHKVSRS FSLVIQQLNT ELRNAVCVFY LVLRALDTVE DDTSIPTDEK VPILIAFHRH IYDTDWHYSC GTKEYKILMD QFHHVSAAFL ELEKGYQEAI EEITRRMGAG MAKFICQEVE TVDDYDEYCH YVAGLVGLGL SKLFLAAGSE VLTPDWEAIS NSMGLFLQKT NIIRDYLEDI NEIPKSRMFW PREIWGKYAD KLEDLKYEEN TNKSVQCLNE MVTNALMHIE DCLKYMVSLR DPSIFRFCAI PQIMAIGTLA LCYNNEQVFR GVVKLRRGLT AKVIDRTKTM ADVYGAFYDF SCMLKTKVDK NDPNASKTLN RLEAVQKLCR DAGVLQNRKS YVNDKGQPNS VFIIMVVILL AIVFAYLRAN
Sequence Positions
1-410
Chromosome Location
Chromosome: 4; NC_003075.7 (16538282..16541926). Location: chromosome: 4
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
47,142 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
Squalene synthase
NCBI/Uniprot Data
NCBI Accession #
NP_195190.1
NCBI GI #
15236168
NCBI GenBank Nucleotide #
NM_119630.3
NCBI GeneID
829616
NCBI Official Full Name
Squalene synthase
NCBI Official Symbol
SQS1
NCBI Official Synonym Symbols
ERG9; SQS1; SQUALENE SYNTHASE; squalene synthase 1; T4L20.220; T4L20_220
NCBI Protein Information
Squalene synthase
NCBI Summary
Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.
UniProt Gene Name
SQS1
UniProt Synonym Gene Names
SQS; SS
UniProt Protein Name
Squalene synthase
UniProt Synonym Protein Names
FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase
UniProt Entry Name
FDFT_ARATH
UniProt Primary Accession #
P53799
UniProt Related Accession #
P53799
UniProt Comments
Catalytic activity: 2 farnesyl diphosphate + NAD(P)H = squalene + 2 diphosphate + NAD(P)+.Cofactor: Magnesium.Pathway: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity. Tissue specificity: Expressed in all tissues analyzed (inflorescences, leaves, stems and roots). Highly expressed in roots.Sequence similarities: Belongs to the phytoene/squalene synthase family.
For research use only, not for clinical use.