NCBI Accession #
NP_174086.1
NCBI GenBank Nucleotide #
NM_102530.3
NCBI Official Full Name
U2 snRNP auxiliary factor small subunit
NCBI Official Symbol
ATU2AF35A
NCBI Official Synonym Symbols
T22C5.30
NCBI Protein Information
U2 snRNP auxiliary factor small subunit
NCBI Summary
U2 auxiliary factor small subunit. The atU2AF35a protein and its homolog, atU2AF35b, contain most of the conserved domains of hsU2AF35, including the psiRRM, one RS domain, two zinc fingers, and the two regions for interacting with U2AF large subunit. Both proteins lack the stretch of glycines present in human U2AF35. The sequences are overall 83% identical, and each Arabidopsis homolog shows approximately 70% similarity to hsU2AF35. U2AF(35) homologs were also identified from maize, rice and other plants with large-scale EST projects. Both genes are expressed in all major tissues, with atU2AF(35)a expressed at a higher level than atU2AF(35)b in most tissues. The expression patterns were different in roots: atU2AF(35)b expressed strongly in whole young roots and root tips and atU2AF(35)a limited to root vascular regions.
UniProt Gene Name
U2AF35A
UniProt Synonym Gene Names
AUSA; U2 snRNP auxiliary factor small subunit A; AtC3H8
UniProt Protein Name
Splicing factor U2af small subunit A
UniProt Synonym Protein Names
U2 auxiliary factor 35 kDa subunit A; U2 small nuclear ribonucleoprotein auxiliary factor small subunit A; U2 snRNP auxiliary factor small subunit A; Zinc finger CCCH domain-containing protein 8; AtC3H8
UniProt Primary Accession #
Q9S709
UniProt Secondary Accession #
Q945S1
UniProt Related Accession #
Q9S709
UniProt Comments
Necessary for the splicing of pre-mRNA . Probably active at the 3' splice sites.