NCBI Accession #
NP_001331261.1
NCBI GenBank Nucleotide #
NM_001343804.1
NCBI Official Full Name
long-chain base (LCB) kinase 1
NCBI Official Symbol
LCBK1
NCBI Official Synonym Symbols
ATLCBK1; K19M13.8; K19M13_8; long-chain base (LCB) kinase 1; SPHINGOSINE KINASE
NCBI Protein Information
long-chain base (LCB) kinase 1
NCBI Summary
Encodes a sphingosine kinase that specifically phosphorylates D-erythro-dihydrosphingosine (DHS), but not N-acetyl-DHS or D-threo-DHS. It also also phosphorylates D-erythro-sphingosine, trans-4, trans-8-sphingadienine and phytosphingosine.
UniProt Synonym Gene Names
AtLCBK1; LCB kinase 1
UniProt Protein Name
Sphingoid long-chain bases kinase 1
UniProt Synonym Protein Names
Sphingosine kinase 1
UniProt Primary Accession #
Q9LRB0
UniProt Secondary Accession #
Q9FHL3; B9DHC8
UniProt Related Accession #
Q9LRB0
UniProt Comments
Involved in the production of sphingolipid metabolites. Active on sphingosine, phytosphingosine (PHS, 4-hydroxysphinganine), D-erythro-dihydrosphingosine, D-erythro-sphingosine and trans-4, trans-8-sphingadienine, an LCB found exclusively in plants, but not on N-acetyl-dihydrosphingosine (C2-dihydroceramide) and D-threo-dihydrosphingosine.