NCBI Accession #
NP_177122.2
NCBI GenBank Nucleotide #
NM_105632.5
NCBI Official Full Name
sphingoid base hydroxylase 1
NCBI Official Symbol
SBH1
NCBI Official Synonym Symbols
F24J1.22; sphingoid base hydroxylase 1
NCBI Protein Information
sphingoid base hydroxylase 1
NCBI Summary
Encodes one of the two redundant sphingoid base hydroxylases (SBH). Involved in sphingolipid trihydroxy long-chain base (4-hydroxysphinganine) biosynthesis. Double mutants of SBHs were dwarfed and not able to progress from vegetative to reproductive growth.
UniProt Protein Name
Sphinganine C4-monooxygenase 1
UniProt Synonym Protein Names
Sphingoid C4-hydroxylase 1; Sphingoid base hydroxylase 1
UniProt Primary Accession #
Q8VYI1
UniProt Secondary Accession #
Q9FWZ2
UniProt Related Accession #
Q8VYI1
UniProt Comments
Involved in sphingolipid trihydroxy long-chain base (4-hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino-1,3,4-trihydroxyoctadecane and -eicosane).