NCBI Accession #
NP_198067.1
NCBI GenBank Nucleotide #
NM_122597.3
NCBI Official Full Name
Na+/H+ exchanger 1
NCBI Official Symbol
NHX1
NCBI Official Synonym Symbols
AT-NHX1; ATNHX; ATNHX1; NA(+)/H(+) ANTIPORTER; Na+/H+ exchanger 1; T21B4.60; T21B4_60
NCBI Protein Information
Na+/H+ exchanger 1
NCBI Summary
Encodes a vacuolar sodium/proton antiporter involved in salt tolerance, ion homeostasis, and leaf development.
UniProt Synonym Gene Names
NHE-1
UniProt Protein Name
Sodium/hydrogen exchanger 1
UniProt Synonym Protein Names
Na(+)/H(+) exchanger 1; NHE-1
UniProt Primary Accession #
Q68KI4
UniProt Secondary Accession #
O04655; Q8LRL1; Q9ZPK3
UniProt Related Accession #
Q68KI4
UniProt Comments
Acts in low affinity electroneutral exchange of protons for cations such as Na+ or K+ across membranes. Can also exchange Li+ and Cs+ with a lower affinity. Involved in vacuolar ion compartmentalization necessary for cell volume regulation and cytoplasmic Na+ detoxification. Required during leaves expansion, probably to stimulate epidermal cell expansion. Confers competence to grow in high salinity conditions.