NCBI Accession #
NP_566843.1
NCBI GenBank Nucleotide #
NM_113839.4
NCBI Official Full Name
SNF1 kinase homolog 11
NCBI Official Symbol
KIN11
NCBI Official Synonym Symbols
AKIN11; ATKIN11; SNF1 kinase homolog 11; SNF1-RELATED PROTEIN KINASE; SNF1-RELATED PROTEIN KINASE 1.2; SNRK1.2
NCBI Protein Information
SNF1 kinase homolog 11
NCBI Summary
encodes a SNF1-related protein kinase that physically interacts with SCF subunit SKP1/ASK1 and 20S proteosome subunit PAD1. It has also been shown to interact with the WD protein PDL1.
UniProt Synonym Gene Names
SNF1; SNRK1.2; AKIN11; AKINalpha1
UniProt Protein Name
SNF1-related protein kinase catalytic subunit alpha KIN11
UniProt Synonym Protein Names
AKIN alpha-1; AKINalpha1
UniProt Primary Accession #
P92958
UniProt Secondary Accession #
P92968; Q3E7R4; A6XGQ9
UniProt Related Accession #
P92958
UniProt Comments
Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase. In vitro, KIN11 exhibits kinase activity on sucrose phosphate synthase and the kinase activity is inhibited by PRL1. May be a subunit of a SCF ubiquitin ligase complex and thus be involved in proteasomal ubiquitination. Involved in innate antiviral defenses.