SKP1-like protein 1A (SKP1A), Recombinant Protein
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SKP1-like protein 1A (SKP1A), Recombinant Protein

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Cat: RP04054
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana SKP1-like protein 1A (SKP1A)
Product Gene Name
SKP1A recombinant protein
Product Synonym Gene Name
SKP1A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSAKKIVLKS SDGESFEVEE AVALESQTIA HMVEDDCVDN GVPLPNVTSK ILAKVIEYCK RHVEAAASKA EAVEGAATSD DDLKAWDADF MKIDQATLFE LILAANYLNI KNLLDLTCQT VADMIKGKTP EEIRTTFNIK NDFTPEEEEE VRRENQWAFE
Sequence Positions
1-160, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
17,857 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
SKP1-like protein

NCBI/Uniprot Data

NCBI Accession #
NP_565123.1
NCBI GI #
18410982
NCBI GenBank Nucleotide #
NM_106245.5
NCBI GeneID
843928
NCBI Official Full Name
S phase kinase-associated protein 1
NCBI Official Symbol
SKP1
NCBI Official Synonym Symbols
ARABIDOPSIS SKP1 HOMOLOGUE 1; ASK1; ATSKP1; S phase kinase-associated protein 1; SKP1A; T4O12.17; T4O12_17; UFO INTERACTING PROTEIN 1; UIP1
NCBI Protein Information
S phase kinase-associated protein 1
NCBI Summary
SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.
UniProt Gene Name
SKP1A
UniProt Synonym Gene Names
SKP1-like 1
UniProt Protein Name
SKP1-like protein 1A
UniProt Synonym Protein Names
UFO-binding protein 1
UniProt Primary Accession #
Q39255
UniProt Secondary Accession #
P92992
UniProt Comments
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling. Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division. Contributes to the correct chromosome segregation during tetrad formation.

For research use only, not for clinical use.