Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (PP2A3), Recombinant Protein
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Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (PP2A3), Recombinant Protein

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Cat: RP04702
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (PP2A3)
Product Gene Name
PP2A3 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MGANSLPTDA TLDLDEQISQ LMQCKPLSEQ QVRALCEKAK EILMDESNVQ PVKSPVTICG DIHGQFHDLA ELFRIGGKCP DTNYLFMGDY VDRGYYSVET VTLLVGLKVR YPQRITILRG NHESRQITQV YGFYDECLRK YGNANVWKIF TDLFDYFPLT ALVESEIFCL HGGLSPSIET LDNIRNFDRV QEVPHEGPMC DLLWSDPDDR CGWGISPRGA GYTFGQDISE QFNHTNNLKL IARAHQLVMD GFNWAHEQKV VTIFSAPNYC YRCGNMASIL EVDDCRNHTF IQFEPAPRRG EPDVTRRTPD YFL
Sequence Positions
1-313, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
35,767 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Serine/threonine-protein phosphatase

NCBI/Uniprot Data

NCBI Accession #
NP_567066.1
NCBI GI #
18410971
NCBI GenBank Nucleotide #
NM_115712.4
NCBI GeneID
825019
NCBI Official Full Name
protein phosphatase 2A-4
NCBI Official Symbol
PP2A-4
NCBI Official Synonym Symbols
EP7; PP2A-3; protein phosphatase 2A-3; protein phosphatase 2A-4; SER/THR PROTEIN PHOSPHATASE
NCBI Protein Information
protein phosphatase 2A-4
NCBI Summary
Encodes one of the isoforms of the catalytic subunit of protein phosphatase 2A: AT1G59830/PP2A-1, AT1G10430/PP2A-2, At2g42500/PP2A-3, At3g58500/PP2A-4 [Plant Molecular Biology (1993) 21:475-485 and (1994) 26:523-528; Note that in more recent publications, there is mixed use of gene names for PP2A-3 and PP2A-4 - some refer to At2g42500 as PP2A-3 and some as PP2A-4].
UniProt Gene Name
PP2A4
UniProt Protein Name
Serine/threonine-protein phosphatase PP2A-4 catalytic subunit
UniProt Synonym Protein Names
Protein phosphatase 2A isoform 4
UniProt Primary Accession #
P48578
UniProt Secondary Accession #
Q9M2G6
UniProt Related Accession #
P48578
UniProt Comments
Functions redundantly with PP2A3, and is involved in establishing auxin gradients, apical-basal axis of polarity and root and shoot apical meristem during embryogenesis. May dephosphorylate PIN1 and regulate its subcellular distribution for polar auxin transport (PubMed:23167545). The holoenzyme composed of PP2AA1, PP2A4 and B'ZETA or B'ETA acts as negative regulator of plant innate immunity by controlling BAK1 phosphorylation state and activation in surface-localized immune receptor complexes (PubMed:25085430).

For research use only, not for clinical use.